Now in its fourth edition, Principles of Tissue Engineering has been the definite resource in the field of tissue engineering for more than a decade. The fourth edition provides an update on this rapidly progressing field, combining the prerequisites for a general understanding of tissue growth and development, the tools and theoretical information needed to design tissues and organs, as well as a presentation by the world's experts of what is currently known about each specific organ system. As in previous editions, this book creates a comprehensive work that strikes a balance among the diversity of subjects that are related to tissue engineering, including biology, chemistry, material science, and engineering, among others, while also emphasizing those research areas that are likely to be of clinical value in the future.

This edition includes greatly expanded focus on stem cells, including induced pluripotent stem (iPS) cells, stem cell niches, and blood components from stem cells. This research has already produced applications in disease modeling, toxicity testing, drug development, and clinical therapies.  This up-to-date coverage of stem cell biology and other emerging technologies -such as brain-machine interfaces for controlling bionics and neuroprostheses- is complemented by a series of new and updated chapters on recent clinical experience in applying tissue engineering, as well as a new section on the application of tissue-engineering techniques for food production. The result is a comprehensive textbook that will be useful to students and experts alike.

• Includes new chapters on biomaterial-protein interactions, nanocomposite and three-dimensional scaffolds, skin substitutes, spinal cord, vision enhancement, and heart valves
• Offers expanded coverage of adult and embryonic stem cells of the cardiovascular, hematopoietic, musculoskeletal, nervous, and other organ systems
• Full-color presentation throughout

INTRODUCTION TO TISSUE ENGINEERING -
PART ONE: THE BASIS OF GROWTH AND DIFFERENTIATION
PART TWO: IN VITRO CONTROL OF TISSUE DEVELOPMENT 
PART THREE: IN VIVO SYNTHESIS OF TISSUES AND ORGANS
PART FOUR: MODELS FOR TISSUE ENGINEERING
PART FIVE: BIOMATERIALS IN TISSUE ENGINEERING
PART SIX: TRANSPLANTATION OF ENGINEERED CELLS AND TISSUES
PART SEVEN: STEM CELLS 
PART EIGHT: GENE THERAPY
PART NINE: BREAST
PART TEN: CARDIOVASCULAR SYSTEM
PART ELEVEN: ENDOCRINOLOGY AND METABOLISM
PART TWELVE: GASTROINTESTINAL SYSTEM
PART THIRTEEN: HEMATOPOIETIC SYSTEM
PART FOURTEEN: KIDNEY AND GENITOURINARY SYSTEM
PART FIFTEEN: MUSCULOSKELETAL SYSTEM
PART SIXTEEN: NERVOUS SYSTEM
PART SEVENTEEN: OPHTHALMIC APPLICATIONS
PART EIGHTEEN: ORAL/DENTAL APPLICATIONS
PART NINETEEN: RESPIRATORY SYSTEM
PART TWENTY: SKIN
PART TWENTY-ONE: CLINICAL EXPERIENCE
PART TWENTY-TWO: REGULATION AND ETHICS