Cellular and Molecular Pathobiology of Cardiovascular Disease focuses on the pathophysiology of common cardiovascular disease in the context of its underlying mechanisms and molecular biology. This book has been developed from the editors' experiences teaching an advanced cardiovascular pathology course for PhD trainees in the biomedical sciences, and trainees in cardiology, pathology, public health, and veterinary medicine. No other single text-reference combines clinical cardiology and cardiovascular pathology with enough molecular content for graduate students in both biomedical research and clinical departments.

The text is complemented and supported by a rich variety of photomicrographs, diagrams of molecular relationships, and tables. It is uniquely useful to a wide audience of graduate students and post-doctoral fellows in areas from pathology to physiology, genetics, pharmacology, and more, as well as medical residents in pathology, laboratory medicine, internal medicine, cardiovascular surgery, and cardiology.

1. Molecular Basis of Cardiac Development 2. Cardiac Metabolism in Health and Disease 3. Cardiac Atrophy & Remodeling 4. The Pathophysiology of Cardiac Hypertrophy and Heart Failure 5. Ischemic Heart Disease and its Consequences 6. Pathophysiology of Cardiomyopathies 7. Cellular and Molecular Pathobiology of the Cardiac Conduction System 8. Molecular Pathobiology of Myocarditis 9. Calcific and Degenerative Heart Valve Disease 10. Vasculogenesis and Angiogenesis 11. Diseases of Medium-sized and Small Vessels 12. Pathophysiology of Atherosclerosis 13. Genetic Diseases of the Aorta (Including Aneurysms) 14. Blood Pressure Regulation and Pathology 15. Venous and Arterial Thrombosis 16. The Pericardium and its Diseases

Computational Materials Science provides the theoretical basis necessary for understanding atomic surface phenomena and processes of phase transitions, especially crystallization, is given. The most important information concerning computer simulation by different methods and simulation techniques for modeling of physical systems is also presented. A number of results are discussed regarding modern studies of surface processes during crystallization. There is sufficiently full information on experiments, theory, and simulations concerning the surface roughening transition, kinetic roughening, nucleation kinetics, stability of crystal shapes, thin film formation, imperfect structure of small crystals, size dependent growth velocity, distribution coefficient at growth from alloy melts, superstructure ordering in the intermetallic compound.

Computational experiments described in the last chapter allow visualization of the course of many processes and better understanding of many key problems in Materials Science. There is a set of practical steps concerning computational procedures presented. Open access to executable files in the book make it possible for everyone to understand better phenomena and processes described in the book.