The revisions of both DSM-IV and ICD-10 have again focused the interest of the field of psychiatry and clinical psychology on the questions of nosology. This book reviews issues within psychiatric nosology from clinical, historical and particularly philosophical perspectives. It brings together an interdisciplinary group of distinguished authors.

• Part I: Nature of Psychiatric Illness


• 1: Kenneth S. Kendler: Introduction to Clinical significance', disability and biomarkers: shifts in thinking between DSM-4 and DSM-5


• 2: Derek Bolton: Clinical significance', disability and biomarkers: shifts in thinking between DSM-4 and DSM-5


• 3: Peter Zachar: Distinguishing but not Dissociating Psychiatric Disorder and Impairment in Functioning: Bolton, Hume, and Sentiment


• 4: Kenneth S. Kendler and Josef Parnas: Introduction to The Hard Question in Psychiatric Nosology


• 5: Eric Turkheimer: The Hard Question in Psychiatric Nosology


• 6: Denny Borsboom: Representation and explanation in psychometric modeling


• 7: Kenneth S. Kendler: Introduction to Obsessive-compulsive and related disorders in DSM-5, ICD-11 and RDoC: Conceptual questions and practical solutions


• 8: Dan Stein: Obsessive-compulsive and related disorders in DSM-5, ICD-11 and RDoC: Conceptual questions and practical solutions


• 9: Miriam Solomon: Obsessive-compulsive and related disorders in DSM-5, ICD-11 and RDoC: Conceptual questions and practical solutions


• 10: Kenneth S. Kendler: Introduction to Mental disorders, network models, and dynamical systems


• 11: Denny Borsboom: Mental disorders, network models, and dynamical systems


• 12: Eric Turkheimer: I Bet on Borsboom


• Part II: Reification, Epidemics, and Individual Symptoms


• 13: Josef Parnas: Introduction to On Reification of Mental Illness: Historical and Conceptual Issues From Emil Kraepelin and Eugen Bleuler to DSM-5


• 14: Paul Hoff: On Reification of Mental Illness: Historical and Conceptual Issues From Emil Kraepelin and Eugen Bleuler to DSM-5


• 15: Dan Stein: Reification of mental illness: Some considerations


• 16: Kenneth S. Kendler: Introduction to Factors in the Development of Psychiatric Epidemics


• 17: Michael First: Factors in the Development of Psychiatric Epidemics


• 18: Josef Parnas: Diagnostic epidemics and diagnostic disarray: the issue of differential diagnosis


• 19: Kenneth S. Kendler: Introduction to Description and Explanation of the Culture bound Syndromes


• 20: Dominic Murphy: Description and Explanation of the Culture bound Syndromes


• 21: Paul Appelbaum: Reflections on Culture-Bound Syndromes


• 22: Kenneth S. Kendler: Introduction to On the Appearance and Disappearance of Asperger's Syndrome


• 23: Miriam Solomon: On the Appearance and Disappearance of Asperger's Syndrome


• 24: Michael First: Impact of "Severity Decategorization" in DSM-5


• 25: Kenneth S. Kendler: Introduction to The ontology and epistemology of symptoms: The case of auditory verbal hallucinations in schizophrenia


• 26: Josef Parnas: The ontology and epistemology of symptoms: The case of auditory verbal hallucinations in schizophrenia


• 27: Paul Hoff: Comment on The Ontology and Epistemology of Symptoms: The Case of Auditory Verbal Hallucinations in Schizophrenia


• Part III: Epistemic Iteration


• 28: Kenneth S. Kendler: Introduction to Epistemic Iteration and Natural Kinds: Realism and Pluralism in Taxonomy


• 29: Hasok Chang: Epistemic Iteration and Natural Kinds: Realism and Pluralism in Taxonomy


• 30: Kenneth S. Kendler: Psychiatric Nosology, Epistemic Iteration and Pluralism


• 31: Kenneth S. Kendler: Introduction to Validity and the causal structure of a disorder


• 32: Joseph Campbell: Validity and the causal structure of a disorder


• 33: Dominic Murphy: Saving the Explananda


• 34: Kenneth S. Kendler: Introduction to Epistemic Iteration or Paradigm Shift: The Case of Personality Disorder


• 35: Peter Zachar: Epistemic Iteration or Paradigm Shift: The Case of Personality Disorder


• 36: Joseph Campbell: Why we should be realists about psychiatric disorders- reply to Peter Zachar


• 37: Josef Parnas: Introduction to Progressive Validation of Psychiatric Syndromes: The Example of Panic Disorder


• 38: Kenneth S. Kendler: Progressive Validation of Psychiatric Syndromes: The Example of Panic Disorder


• 39: Kenneth S. Kendler: Comments on Kenneth S. Kendler's"Progressive Validation of Psychiatric Syndromes: The Example of Panic Disorder"


• Part IV: Descriptive to Etiologic and Living Document


• 40: Josef Parnas: Introduction to Causal Pathways, Random Walks and Tortuous Paths: Moving from the Descriptive to the Etiological in Psychiatry


• 41: Kenneth Schaffner and Kathryn Tabb: Causal Pathways, Random Walks and Tortuous Paths: Moving from the Descriptive to the Etiological in Psychiatry


• 42: Hasok Chang: Notes for commentary on Kathryn Tabb and Kenneth F. Schaffner, "Causal Pathways, Random Walks and Tortuous Paths: Moving from the Descriptive to the Etiological in Psychiatry"


• 43: Kenneth S. Kendler: Introduction to What is progress in psychiatric research?


• 44: Stephan Heckers: What is progress in psychiatric research?


• 45: Derek Bolton: Commentary on Stephan Heckers' "What is progress in psychiatric research?"


• 46: Kenneth S. Kendler: Introduction to DSM-5.1: Perspectives on Continuous Improvement in Diagnostic Frameworks


• 47: Paul Appelbaum: DSM-5.1: Perspectives on Continuous Improvement in Diagnostic Frameworks


• 48: Stephan Heckers: How do we improve the DSM?

Dr. Kendler has pursued for most of his career substantive research in psychiatric genetics and epidemiology. He has, during that time, actively published at the interface between psychiatric genetics and psychiatric nosology. He was on the Task Forces of DSM-III-R and DSM-IV. For DSM-5, he chaired the Scientific Review Committee. He is currently vice-chair of the American Psychiatric Association's DSM Steering Committee which is overseeing changes in DSM-5. He has, over the last 15 years, written extensively on topics at the interface between psychiatry and philosophy including a number of papers on nosology. Along with Dr. Parnas, he edited volumes that included the papers and commentaries for the three prior Philosophy of Psychiatry conferences: i) Philosophical Issues in Psychiatry: Explanation, Phenomenology and Nosology, ii) Philosophical Issues in Psychiatry: II Nosology, and iii) Philosophical Issues in Psychiatry: III: the nature and sources of historical change.
Dr. Parnas has published in the domain of psychopathology, epidemiology and pathogenesis of schizophrenia spectrum disorders. Over the past 25 years he has been active at the interface of psychopathology and philosophy, especially philosophy of mind and phenomenology, applying these to the issues of psychiatric diagnosis and classification. His most recent work deals with experiential trait-phenotypes of the schizophrenia spectrum disorders, in particular the anomalies of self-experience. He is a co-founder of and a senior researcher at an interdisciplinary theoretical institute, Center for Subjectivity Research at the University of Copenhagen, integrating psychiatry, philosophy, and hermeneutics in interaction with cognitive science and neuroscience. Along with Dr. Kendler, he edited three prior volumes on philosophy and psychiatry (vide supra).