Global mental health is a dynamic field of global health; a core aspect of the story which has led to its emergence has been the conduct of randomised controlled trials (RCTs) evaluating innovative delivery systems of packages of care for mental disorders in low-resource settings. Global Mental Health Trials brings together many of the world's leading researchers active in the fields of RCTs in low- and medium-resource counties and settings related to improving mental health care. It presents clear and practical information about how to conduct such trials in these settings, along with critical methodological and ethical issues related to such trials, learning from the positive and negative experiences of expert scientists in many counties worldwide who have completed such trials. This book serves as a valuable resource for practitioners in mental health - psychiatrists, psychiatric nurses nursing, psychologists, social workers, and occupational therapists - as well as researchers in the areas of psycho-social treatments in mental health, mental health services research, and programme and systems evaluation.

Graham Thornicroft, Professor of Community Psychiatry, King's College London, Institute of Psychiatry, Vikram Patel, London School of Hygiene and Tropical Medicine, UK, and Public Health Foundation of India, Goa, India

• PART A: PRINCIPLES OF GLOBAL MENTAL HEALTH TRIALS


• 1: Graham Thornicroft and Vikram Patel: The importance of trials for global mental health


• 2: Lara Fairall, Merrick Zwarenstein, Graham Thornicroft: The applicability of trials of complex mental health interventions


• 3: Abhijit Nadkarni, Mary J De Silva, Vikram Patel: Developing mental health interventions


• 4: Helen Weiss: Design issues in GMH trials in low resource settings


• 5: Paul Bolton and Judith Bass: Defining Relevant Outcomes


• 6: Iris Mosweu and Paul McCrone: Economic evaluations in global mental health


• 7: Theresa S. Betancourt, William Beardslee, Catherine Kirk, Katrina Hann, Moses Zombo, Christine Mushashi, Fredrick Kanyanganzi, Morris Munyana, and Justin I. Bizimana: Working with vulnerable populations


• 8: Athula Sumathipala and Buddhika Fernando: Ethical issues in global mental health trials


• PART B: CASE STUDIES OF GLOBAL MENTAL HEALTH TRIALS (VP leads section)


• 9: Sudipto Chatterjee, Smita Naik, Hamid Dabholkar, Padmavati R, Sujit John, Mirja Koschorke, Rangaswamy Thara: Trials of interventions for people with psychosis


• 10: Neerja Chowdhary, Atif Rahman, Helena Verdeli, Vikram Patel: Trials of interventions for people with depression


• 11: María Elena Medina-Mora; Sairat Noknoy, Cheryl Cherpitel, Tania Real, Román Pérez Velasco, Rodrigo Marín Navarrete, Nancy Amador, Viviana E Horigian: Trials of interventions for people with alcohol use disorders


• 12: Amit Dias, Dilip Motghare, Daisy Acosta, Jacob Roy, Jotheeswaran AT, Ralph N Martins: Trials of interventions for people with dementia


• 13: Wietse A. Tol; Mark J.D. Jordans; Dessy Susanty; Joop T.V.M. de Jong: Trials for mental disorders and conditions associated with stress


• 14: Lakshmi Vijayakumar, Melissa Pearson and Shuba Kumar: Suicide prevention trials


• PART C: BEYOND TRIALS: REDUCING THE MENTAL HEALTH TREATMENT GAP


• 15: David McDaid: Economic modelling for global mental health


• 16: Mary J De Silva, Alex Cohen, Vikram Patel: Evaluation of interventions in the real world