This issue of Anesthesiology Clinics, guest edited by Drs. Lee Fleisher and Jesse Raiten, focuses on This issue of Anesthesiology Clinics, guest edited by Drs. Alison Perate and Vanessa Olbrecht, focuses on Anesthesiologists in time of disaster. This is one of four issues each year selected by the series consulting editor, Dr. Lee Fleisher. Articles in this issue include, but are not limited to: Development of an Anesthesiology Disaster Response Plan; The Initial Response to a Pandemic- Anesthesiology Experiences from China at the Onset of Covid19; Development of a Critical Care Response- Experiences from Italy during the Covid19 Pandemic; Anesthesiology and Critical Care Response to Covid19 in resource limited settings: Experiences from Nepal; Anesthesiology in Times of Physical Disasters- Earthquakes, Typhoons, Tsunamis; Mass Casualty and the Role of the Anesthesiologist; Anesthesiology in the Active War Zone/ Special Operations; Regional Anesthesia in the Field for Trauma Victims; Clinical Research Redirection and Optimization during a Pandemic.