In this issue of Clinics in Liver Disease, guest editor Robert G. Gish brings his considerable expertise to the topic of Hepatitis B and Hepatitis D. The articles provide state-of-the-art clinical summaries of the advances in Hepatitis B and D, with emphasis on HBV viro-immunology, novel assays, new targets, and tests for HBV and HDV, and more.

• Contains 13 relevant, practice-oriented topics including Novel Assays to Solve the Clinical and Scientific Challenges of Chronic Hepatitis B; Maternal-to-Child Transmission of Hepatitis B Virus and Hepatitis Delta Virus; Triple Threat: HDV, HBV, HIV Coinfection; Targeting Hepatitis B Virus DNA Using Designer Gene Editors; and more.

• Provides in-depth clinical reviews on Hepatitis B and D, offering actionable insights for clinical practice.

• Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

Chronic Hepatitis B: Treat all Who Are Viremic?
Are the New Nucleos(t)ide Analogs Better than the Old Nucleos(t)ide Analogs?
What Is the Current Status of Hepatitis B Virus Viro-Immunology?
Novel Assays to Solve the Clinical and Scientific Challenges of Chronic Hepatitis B
Overview of New Targets for Hepatitis B Virus: Immune Modulators, Interferons, Bifunctional Peptides, Therapeutic Vaccines and Beyond
Novel Drug Development in Chronic Hepatitis B Infection: Capsid Assembly Modulators and Nucleic Acid Polymers
Targeting Hepatitis B Virus DNA Using Designer Gene Editors
Maternal-to-Child Transmission of Hepatitis B Virus and Hepatitis Delta Virus
State of the Art: Test all for Anti-Hepatitis D Virus and Reflex to Hepatitis D Virus RNA Polymerase Chain Reaction Quantification
Triple Threat: HDV, HBV, HIV Coinfection
What Is the Real Epidemiology of Hepatitis D Virus and Why so Many Mixed Messages?
What is the Path Forward to Treat Hepatitis Delta Virus?: Old Treatments and New Options
Test All for Hepatitis B Virus: Link to Care and Treatment if Quantitative DNA Positive, Vaccinate if Susceptible