Bültmann & Gerriets
Synthetic Polymers in Drug and Biotherapeutics Delivery
von Rangasamy Jayakumar MD DM MNAMS MRCP (UK) FRCP (Glas), Mar Masson, Deepagan Veerasikku Gopal
Verlag: Elsevier Science & Techn.
Reihe: Woodhead Publishing Series in Biomaterials
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ISBN: 978-0-323-95234-7
Erschienen am 05.10.2024
Sprache: Englisch
Umfang: 450 Seiten

Preis: 215,00 €

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Klappentext
Inhaltsverzeichnis

Synthetic Polymers in Drug and Biotherapeutics Delivery covers new polymers that are fast replacing obsolete polymers in the field of drug delivery. Each chapter focuses on a specific polymer, detailing its design, synthesis, fabrication techniques, and applications in drug and biotherapeutics delivery. Synthetic polymers provide a unique set of opportunities in drug and biotherapeutics delivery due to their chemical versatility and tunable physicochemical properties. Such polymers can be formulated into nanoparticles, nanofibers, nanogels, microparticles, beads, hydrogels, and scaffolds to suit specific needs such as drug release rate, and biodegradation with low toxicity. This book covers new polymers that are fast replacing obsolete polymers in the field of drug delivery. Each chapter will focus on a specific polymer detailing its design, synthesis, fabrication techniques, and applications in drug and biotherapeutics delivery. This book provides a thorough review of the latest research in this rapidly changing field and would be of interest to materials scientists, pharmaceutical scientists, biomedical engineers, chemical engineers, and clinicians with an interest in materials development.
- Details the immunological aspects of synthetic polymeric materials, helping the reader prepare for, and even avoid, unwanted side effects of use
- Reviews each polymer sub-type, chapter-by-chapter, ensuring thorough coverage and detailed analysis of each
- Explores a range of applications in drug and biotherapeutics delivery, including treatments for cardiovascular, neurological and gastrointestinal diseases



1. Role and challenges of synthetic biopolymers in drug/ biotherapeutic delivery 2. Poly(caprolactone) 3. Poly(lactic-co-glycolic acid) in drug delivery and tissue engineering applications 4. Poly(amidoamine)-based dendrimers for biomedical applications 5. pH-responsive synthetic polymers for drug delivery applications 6. Chemistry, properties, and role of polyoxazoline in drug delivery 7. Poly(amides) 8. Polyethyleneimine-based biomaterials for therapy and diagnostic applications 9. Polyethylene glycol: structure, properties, and biomedical applications 10. Poly(N-isopropyl acrylamide): a thermo-responsive polymer for bio-therapeutic applications 11. Poly(2-hydroxyethyl methacrylate): a new leap to accelerate the effective biotherapeutic and drug delivery systems 12. Poly(N-(2-hydroxypropyl)methacrylamide) 13. Polydioxanone in drug delivery 14. Poly(lactide) 15. Blending techniques and formulation strategies 16. Clinical application, regulatory status, and future perspective of synthetic biopolymers in drug/bio-therapeutics delivery


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