Advanced Spectroscopic Methods to Study Biomolecular Structure and Dynamics presents the latest emerging technologies in spectroscopy and advances in established spectroscopic methods. The book presents a guide to research methods in biomolecular spectroscopy, providing comprehensive coverage of developments in the spectroscopic techniques used to study protein structure and dynamics. Seventeen chapters from leading researchers cover key aspects of spectroscopic methods, with each chapter covering structure, folding, and dynamics. This title will help researchers keep up-to-date on the latest novel methods and advances in established methods.

• Presents current, emerging, and evolving advances and applications of spectroscopic techniques in the study of biomolecules, including proteins and nucleic acids
• Discusses contemporary spectroscopic techniques used to study biomolecular structure, interaction, and dynamics

1. Fundamentals of spectroscopy for biomolecular structure and dynamics2. Fluorescence-based techniques to assess biomolecular structure and dynamics3. Structural analysis of biomacromolecules using circular dichroism spectroscopy4. Nuclear magnetic resonance spectroscopy for protein structure, folding, and dynamics5. Advanced NMR spectroscopy methods to study protein structure and dynamics6. Applications of infrared spectroscopy to study proteins7. Raman spectroscopy to study biomolecules, their structures, and dynamics8. Spectroscopic investigation of biomolecular dynamics using light scattering methods9. Protein footprinting by mass spectrometry: H/D exchange, specific amino acid labeling, and fast photochemical oxidation of proteins10. Small angle scattering techniques for biomolecular structure and dynamics11. Advances in X-ray crystallography methods to study structural dynamics of macromolecules12. Spectroscopic methods to study protein folding kinetics: methodology, data analysis, and interpretation13. Spectroscopic methods to study the thermodynamics of biomolecular interactions14. Spectroscopic methods to detect and analyze protein oligomerization, aggregation, and fibrillation15. Multimodal spectroscopic methods for the analysis of carbohydrates16. Integration of spectroscopic and computational data to analyze protein structure, function, folding, and dynamics17. Advance data handling tools for easy, fast, and accurate interpretation of spectroscopic data