Leptomeningeal Metastases is intended to provide the reader with an overview of the state-of-the-art therapy for the cancer patient with leptomeningeal cancer with additional information on epidemiology, symptom management, new clinical trials, and current basic research in animal models for experimental therapies.

Anatomy and Physiology of the Leptomeninges and CSF Space.- Leptomeningeal Neoplasia: Epidemiology, Clinical Presentation, CSF Analysis and Diagnostic Imaging.- Leptomeningeal Metastases from Solid Tumors (Meningeal Carcinomatosis).- Leptomeningeal Metastases from Leukemias and Lymphomas.- Leptomeningeal Metastasis of Primary Central Nervous System (CNS) Neoplasms.- Leptomeningeal Cancer in the Pediatric Patient.- Neurosurgical Interventions for Leptomeningeal Tumor.- Current Treatment of Leptomeningeal Metastases: Systemic Chemotherapy, Intrathecal Chemotherapy and Symptom Management.- Radiation Therapy for Leptomeningeal Cancer.- Animal Models of Leptomeningeal Cancer.- Improving the Outcome of Patients with Leptomeningeal Cancer: New Clinical Trials and Experimental Therapies.