Landmarks and Advances in Translational Lymphology.- Embryonic Development of the Lymphovascular System and Tumor Lymphangiogenesis.- Lymphatic Origin from Embryonic Stem Cells.- Lymphatic Markers, Tumour Lymphangiogenesis and Lymph Node Metastasis.- Anatomy of the Human Lymphatic System.- SPECT-CT Fusion Imaging Radionuclide Lymphoscintigraphy: Potential for Limb Lymphedema Assessment and Sentinel Node Detection In Breast Cancer.- Sentinel Node Identification using Radionuclides in Melanoma and Breast Cancer.- Targeted Introduction of Substances into the Lymph Nodes for Endolymphatic Therapy.- Mechanisms of Metastasis: Seed and Soil.- Preclinical Models of Regional Lymph Node Tumor Metastasis.- A New Breast Cancer Model for Lymphatic Metastasis.- Lymph Node Micrometastases in Lung Cancer.- Effects of Chemokines on Tumor Metastasis.- Regional Lymph Node Metastases, a Singular Manifestation of the Process of Clinical Metastases in Cancer: Contemporary Animal Research And Clinical Reports Suggest Unifying Concepts.- Patterns of Metastatsis in Head and Neck Cancer.- Patterns of Metastasis in Human Solid Cancers.- Significance of Regional Draining Lymph Nodes in the Development of Tumor Immunity: Implications for Cancer Immunotherapy.- Targeting Small Molecules in Cancer.- Update on the Role of EGFR Inhibitors in Cancer Therapeutics.- New Promises in the Adjuvant, and Palliative Treatment of Melanoma.- Future Perspectives and Unanswered Questions on Cancer Metastasis and the Lymphovascular System.

This book details the anatomy and physiology of the lymphovascular system as well as describes the mechanisms of metastasis. It provides readers with an understanding of immune responses of draining lymph nodes against cancer. Coverage also explains the rationale of adopting molecular therapeutics against growth factor receptors, apoptotic factors, signaling pathways and angiogenesis.