In this issue of Clinics in Laboratory Medicine, guest editor Dr. Linoj Samuel brings his considerable expertise to the topic of Point of Care Testing. Top experts discuss the challenges, techniques, and data collection for point of care and at-home testing options for COVID-19, fungal pathogens, and STDs in various demographics, among other key topics.
- Contains 10 practice-oriented topics including point of care testing during the COVID-19 pandemic: challenges and pitfalls; will antigen testing remain relevant in point of care testing; the role of point of care testing in specific populations; lab at home: is at-home testing the new normal; point of care testing for sexually transmitted diseases; and more. 
- Provides in-depth clinical reviews on point of care testing, offering actionable insights for clinical practice. 
- Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews. 

Regulatory Approach to Point-of-Care/At-Home Testing in the United StatesPractical Challenges of Point-of-Care TestingWill Antigen Testing Remain Relevant in the Point-of-Care Testing Environment?The Role of Point-of-Care Testing in Specific PopulationsPoint-of-Care Testing for Sexually Transmitted InfectionsPoint-of-Care Testing for the Diagnosis of Fungal Infections: Current Testing Applications and Potential for the FutureMetaplastic Breast Carcinoma Revisited; Subtypes Determine Outcomes:Comprehensive Pathologic, Clinical, and Molecular ReviewUpdate on Ovarian Sex Cord-Stromal TumorsKidney Tumors: New and Emerging Kidney Tumor EntitiesA New Landscape of Testing and Therapeutics in Metastatic Breast Cancer