In this issue of PET Clinics, guest editors Drs. Abass Alavi, Habib Zaidi, and Suleman Surti bring their considerable expertise to the topic of Advances in Organ-specific PET Instrumentation and Their Clinical Applications. Top experts cover key topics such as the increasing use of silicon photomultiplier (SiPM) technology, advances in depth-of-interaction (DOI) and time-of-flight (TOF) PET detectors, the use of artificial intelligence technologies for detector development; and more.

• Contains 11 relevant, practice-oriented topics including advances in PET detectors and readout technologies; whole-gamma imaging; clinical applications of dedicated brain PET; clinical applications of dedicated breast PET; potential clinical applications of dedicated prostate PET; and more.
• Provides in-depth clinical reviews on advances in organ-specific PET instrumentation and their clinical applications, offering actionable insights for clinical practice.
• Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

Advancements in Positron Emission Tomography Detectors: From Silicon Photomultiplier Technology to Artificial Intelligence Applications
New Horizons in Brain PET Instrumentation
Advances in Breast PET Instrumentation
Developments in Dedicated Prostate PET Instrumentation
Innovations in Small-Animal PET Instrumentation
High-resolution Imaging Using Virtual-Pinhole PET Concept
Whole Gamma Imaging: Challenges and Opportunities
Transforming Neurology and Psychiatry: Organ-specific PET Instrumentation and Clinical Applications
Clinical Applications of Dedicated Breast Positron Emission Tomography
Potential Clinical Applications of Dedicated Prostate Positron Emission Tomography