In this text, Nicholas Rescher illustrates the limits that confront our efforts to advance the frontiers of knowledge.

1. Asking for more than truth: Duhem's law of cognitive complementarity; 2. Kant's conception of knowledge as systemized information; 3. Spencer's law of cognitive development; 4. Gibbon's Law of logarithmic returns; 5. Adams's thesis on exponential growth; 6. Quality retardation; 7. How much can be known? A Leibnizian perspective on the quantitative discrepancy between linguistic truth and objective fact; 8. On the limits of knowledge: a Kantian perspective on cognitive finitude.