Covers each physiological MR methodology and their applications to all major neurological diseases.

Introduction; Part I. Physiological MR Techniques: 1. Fundamentals of MR spectroscopy; 2. Quantification and analysis in MR spectroscopy; 3. Artifacts and pitfalls in MR spectroscopy; 4. Fundamentals of diffusion MR imaging; 5. Human white matter anatomical information revealed by diffusion tensor imaging and fiber tracking; 6. Artifacts and pitfalls in diffusion MR imaging; 7. Cerebral perfusion imaging by exogenous contrast agents; 8. MRI detection of regional blood flow using arterial spin labelling; 9. Imaging perfusion and blood-brain barrier permeability using T1-weighted dynamic contrast-enhanced MRI; 10. Susceptibility weighted imaging; 11. Artifacts and pitfalls in perfusion MR imaging; 12. fMRI - methodologies, practicalities and pitfalls; Part II. Cerebrovascular Disease: 13. Cerebrovascular disease: overview; 14. MR spectroscopy in stroke; 15. Diffusion and perfusion MR in stroke; 16. Arterial spin labelling in stroke; 17. MR diffusion tensor imaging in stroke; 18. MR spectroscopy in severe obstructive carotid artery disease; 19. Perfusion and diffusion imaging in chronic carotid disease; 20. Susceptibility imaging and stroke; Part III. Adult Neoplasia: 21. Adult neoplasia: overview; 22. MRS in adult neoplasia; 23. Diffusion MR imaging in adult neoplasia; 24. Perfusion MR imaging in adult neoplasia; 25. Permeability imaging in adult neoplasia; 26. Functional MRI in presurgical planning; Part IV. Infection, Inflammation and Demyelination: 27. Physiological imaging in infection, inflammation and demyelination: overview; 28. MR spectroscopy in intracranial infection; 29. Diffusion and perfusion MR imaging of intracranial infection; 30. MR spectroscopy in demyelination and inflammation; 31. Diffusion and perfusion MRI in inflammation and demyelination; 32. Physiological MR to evaluate HIV-associated brain disorders; Part V. Seizure Disorders: 33. Seizure disorders; 34. MR spectroscopy in seizure disorders; 35. Diffusion and perfusion MR imaging in seizure disorders; Part VI. Psychiatric and Neurodegenerative Diseases: 36. Psychiatric and neurodegenerative disease: overview; 37. MR spectroscopy in psychiatry; 38. Diffusion MR imaging in neuropsychiatry and aging; 39. 1H MR spectroscopy in aging and dementia; 40. Physiological MR in neurodegenerative diseases; 41. Iron imaging in neurodegenerative disorders; Part VII. Trauma: 42. Potential role of MR spectroscopy, diffusion-weighted/diffusion tensor imaging and perfusion imaging in traumatic brain injury: overview; 43. MR spectroscopy in traumatic brain injury; 44. Diffusion and perfusion-weighted MR imaging in head injury; 45. Susceptibility weighted imaging in traumatic brain injury; Part VIII. Pediatrics: 46. Physiological MR of the pediatric brain: overview; 47. Physiological MRI of normal development and developmental delay; 48. MR spectroscopy in hypoxic brain injury; 49. The role of diffusion and perfusion weighted brain imaging in neonatology; 50. Physiological MR of pediatric brain tumors; 51. Physiological MRI techniques and pediatric stroke; 52. MR spectroscopy in pediatric white matter disease; 53. MR spectroscopy of inborn errors of metabolism; 54. Pediatric trauma; 55. Physiological MR of the spine; Index.