"When fertilization in vitro was developed by the pioneers, Dr. Robert G. (Bob) Edwards, Miss Jean Purdy, and Dr. Patrick Steptoe, their primary focus was to obtain oocytes that could be successfully fertilized in laboratory conditions. Embryo culture and embryo selection were just secondary aims at that time. In the early 1970s, the first attempts to obtain a pregnancy after IVF were in cycles in which ovarian stimulation was performed by administration of human menopausal gonadotropins (hMG)"--

1. Introduction: why do we bother with embryo selection? Arne Sunde and Kersti Lundin; 2. Embryo developmental programming Virginia N. Bolton; 3. Embryo-maternal interactions Lois A. Salamonsen, Tracey A. Edgell, Guiying Nie, and Jemma Evans; 4. The sperm's role in embryo development Nahid Punjani, Russell P. Hayden and Peter N. Schlegel; 5. The Oocyte's role in embryo development David F. Albertini; 6. The laboratory's role in embryo development Dean Morbeck; 7. Handling of gametes and embryos Sharon T. Mortimer; 8. Noninvasive morphological selection of Oocytes Giovanni Coticchio, Elena Borini, Catello Scarica, and Andrea Borini; 9. Prospects for bioenergetics for embryo selection Jonathan Van Blerkom; 10. Static morphological assessment for embryo selection Thomas Ebner; 11. Dynamic morphological assessment for embryo selection Alison Campbell; 12. Noninvasive analysis of embryo nutrient utilization for embryo selection David K. Gardner, Laura Ferrick, Rebecca L. Kelley, and Yee Shan Lisa Lee; 13. Genomics for embryo selection Elpida Fragouli and Dagan Wells; 14. Biopsy techniques from polar body to blastocyst Danilo Cimadomo, Nicoletta Barnocchi, Letizia Papini, Federica Innocenti, Filippo Maria Ubaldi and Laura Rienzi; 15. Cell-free DNA analysis for PGT-A Luca Gianaroli, Silvia Azzena and Maria C. Magli; 16. What science may come for embryo selection? Paolo Rinaudo.