A practical review of factors affecting male fertility and the treatments and strategies that can optimize IVF outcomes.

1. Sperm selection for ART success R John Aitken; 2. New horizons in male subfertility and infertility Brett Nixon and Elizabeth G. Bromfield; 3. Chromosome abnormalities and the infertile male Csilla Krausz and Viktoria Rosta; 4. The effect of endocrine disruptors and environmental and lifestyle factors on the sperm epigenome Viviane Santana, Albert Salas-Huetos, Emma R. James and Douglas T. Carrell; 5. Lifestyle factors and sperm quality Ciara Wright; 6. The effect of age on male fertility and the health of offspring Allan Pacey and Sarah Martins da Silva; 7. The assessment and role of anti-sperm antibodies Gary N. Clarke; 8. FSH treatment in male infertility Csilla Krausz, Viktoria Rosta and Alberto Ferlin; 9. Antioxidants to improve sperm quality Elena Martínez Holguín, Enrique Lledó García, Ángel Rebollo Román, Javier González García, José Jara Rascón and Carlos Hernández Fernández; 10. The history of utilization of IVF for male factor subfertility Gabor T Kovacs; 11. The case against intracytoplasmic sperm injection for all David Mortimer and Sharon T. Mortimer; 12. Perinatal outcomes from IVF and ICSI Michael Davies; 13. Artificial insemination with partner's sperm for male subfertility Willem Ombelet; 14. Obstructive azoospermia: is there a place for microsurgical testicular sperm extraction? Ahmad Aboukhshaba, Russell P. Hayden and Peter N. Schlegel. 15. Should varicocele be operated on before IVF? Shannon H.K. Kim and Victoria Nisenblat. 16. Donor insemination - Past, present and future perspective Christopher LR Barratt, Rachel Agnew and Eleanor Heighton; 17. DNA damage in spermatozoa Russell P. Hayden, Ahmad Aboukhshaba and Peter N. Schlegel; 18. Prevention of male infertility from childhood to adulthood Alberto Ferlin