1. Introduction Andrea Boggio,Cesare P. R. Romano and Jessica Almqvist; 2. The governance of human (germline) genome modification at the international and transnational level; Part I. North America: 3. The regulation of human germline genome modification in Canada Erika Kleiderman; 4. The regulation of human germline genome modification in the United States Kerry Lynn Macintosh; 5. The regulation of human germline genome modification in Mexico María de Jesús Medina Arellano; Part II. Europe: 6. The regulation of human germline genome modification in Europe Jessica Almqvist and Cesare P. R. Romano; 7. The regulation of human germline genome modification in the United Kingdom James Lawford Davies; 8. The regulation of human germline genome modification in Germany Timo Faltus; 9. The regulation of human germline genome modification in Belgium Guido Pennings; 10. The regulation of human germline genome modification in Sweden Santa Slokenberga and Heidi Carmen Howard; 11. The regulation of human germline genome modification in the Netherlands Britta van Beers, Charlotte de Kluiver and Rick Maas; 12. The regulation of human germline genome modification in Italy Ludovica Poli; 13. The regulation of human germline genome modification in Spain Iñigo de Miguel Beriain and Carlos María Romeo Casabona; 14. The regulation of human germline genome modification in France Alessandro Blasimme, Dorothée Caminiti and Effy Vayena; 15. The regulation of human germline genome modification in Switzerland Alessandro Blasimme, Dorothée Caminiti and Effy Vayena; Part III. Asia: 16. The regulation of human germline genome modification in Japan Tetsuya Ishii; 17. The regulation of human germline genome modification in The People's Republic of China Lingqiao Song and Rosario Isasi; 18. The regulation of human germline genome modification in The Republic of Korea Hannah Kim and Yann Joly; 19. The regulation of human germline genome modification in Singapore Calvin W. L. Ho; Part IV. Other OECD Countries: 20. The regulation of human germline genome modification in Australia Dianne Nicol; 21. The regulation of human germline genome modification in Israel Vardit Ravitsky and Gali Ben-Or; 22. Towards a human rights framework for the regulation of human germline genome modification Andrea Boggio, Cesare P. R. Romano and Jessica Almqvist.