Complete, up-to-date coverage of the broad area of nucleic acidchemistry and biology
Assembling contributions from a collection of authors withexpertise in all areas of nucleic acids, medicinal chemistry, andtherapeutic applications, Medicinal Chemistry of NucleicAcids presents a thorough overview of nucleic acidchemistry--a rapidly evolving and highly challengingdiscipline directly responsible for the development of antiviraland antitumor drugs. This reliable resource delves into a multitudeof subject areas involving the study of nucleic acids--such asthe new advances in genome sequencing, and the processes forcreating RNA interference (RNAi) based drugs--to assistpharmaceutical researchers in removing roadblocks that hinder theirability to predict drug efficacy. Offering the latest cutting-edgescience in this growing field, Medicinal Chemistry of Nucleic Acidsincludes:
* In-depth coverage of the development and application of modifiednucleosides and nucleotides in medicinal chemistry
* A close look at a large range of current topics on nucleic acidchemistry and biology
* Essential information on the use of nucleic acid drugs to treatdiseases like cancer
* A thorough exploration of siRNA for RNAi and the regulation ofmicroRNA, non-coding RNA (ncRNA), a newly developing and excitingresearch area
Thorough in its approach and promising in its message,Medicinal Chemistry of Nucleic Acids probes the new domainsof pharmaceutical research--and exposes readers to a wealth ofnew drug discovery opportunities emerging in the dynamic field ofnucleic acid chemistry.