Atul B. Mehta and A. Victor Hoffbrand are both at the Royal Free and University College School of Medicine, Royal Free Hospital, London

Preface to the fourth edition 6
 
Preface to the first edition 6
 
Glossary 7
 
Normal values 8
 
About the companion website 9
 
Part 1 Basic physiology and practice
 
1 Haemopoiesis: physiology and pathology 10
 
2 Normal blood cells I: red cells 14
 
3 Normal blood cells II: granulocytes, monocytes and the reticuloendothelial system 18
 
4 Normal blood cells III: lymphocytes 20
 
5 Lymph nodes, the lymphatic system and the spleen 23
 
6 Clinical assessment 24
 
7 Laboratory assessment 26
 
Part 2 Red cell disorders
 
8 General aspects of anaemia 30
 
9 Iron I: physiology and deficiency 33
 
10 Iron II: overload and sideroblastic anaemia 36
 
11 Megaloblastic anaemia I: vitamin B12 (B12) and folate deficiency - biochemical basis, causes 38
 
12 Megaloblastic anaemia II: clinical features, treatment and other macrocytic anaemias 40
 
13 Haemolytic anaemias I: general 42
 
14 Haemolytic anaemias II: inherited membrane and enzyme defects 44
 
15 Haemolytic anaemias III: acquired 46
 
16 Haemolytic anaemias IV: genetic defects of haemoglobin - thalassaemia 48
 
17 Haemolytic anaemias V: genetic defects of haemoglobin - sickle cell disease 52
 
Part 3 Benign disorders of white cells
 
18 Benign disorders of white cells I: granulocytes, monocytes, macrophages 54
 
19 Benign disorders of white cells II: lymphocytes, lymph nodes, spleen, HIV 56
 
Part 4 Haematological malignancies
 
20 Introduction to Haematological malignancy: basic mechanisms 58
 
21 General aspects of treatment 61
 
22 Acute leukaemia I: classifi cation and diagnosis 64
 
23 Acute leukaemia II: treatment and prognosis 68
 
24 Chronic Myeloid Leukaemia (BCR-ABL1 positive) 70
 
25 Myelodysplasia (myelodysplastic syndromes) 72
 
26 Myeloproliferative disorders I: introduction 74
 
27 Myeloproliferative disorders II: polycythaemia rubra vera 76
 
28 Myeloproliferative disorders III: essential thrombocythaemia, primary myelofi brosis and systemic mastocytosis 78
 
29 Chronic lymphocytic leukaemia 80
 
30 Multiple myeloma and plasma cell disorders 83
 
31 Lymphoma I: introduction 86
 
32 Lymphoma II: Hodgkin lymphoma 88
 
33 Lymphoma III: non-Hodgkin lymphoma - aetiology and classification 90
 
34 Lymphoma IV: clinical and laboratory features of more common subtypes 92
 
35 Lymphoma V: treatment and prognosis 94
 
Part 5 Treatment and procedures
 
36 Bone marrow failure 96
 
37 Haematological effects of drugs 98
 
38 Stem cell transplantation 100
 
Part 6 Haemostasis
 
39 Normal haemostasis I: vessel wall and platelets 102
 
40 Normal haemostasis II: coagulation factors and fi brinolysis 104
 
41 Disorders of haemostasis I: vessel wall and platelets 106
 
42 Disorders of haemostasis II: inherited disorders of coagulation 108
 
43 Disorders of haemostasis III: acquired disorders of coagulation 110
 
44 Thrombosis and anti-thrombotic therapy 112
 
45 Anticoagulation 115
 
Part 7 Haematological aspects of tropical disease
 
46 Haematological aspects of tropical diseases 118
 
47 Haematology of pregnancy and infancy 120
 
Part 8 Blood transfusion
 
48 Blood transfusion I 122
 
49 Blood transfusion II 124
 
Appendix: cluster of differentiation nomenclature system 127
 
Index 129

Following the familiar, easy-to-use at a Glance format, Haematology at a Glance, Fourth Edition is a broad and accessible introduction to the study of blood. Fully revised and updated to reflect advances in the field and in clinical practice, this new edition covers essential knowledge, from basic hematological physiology to blood disorders and their diagnosis and treatment.
This new edition of Haematology at a Glance:
* Features expanded sections on the underlying mechanisms, diagnostic techniques and management of the malignant haematological diseases. Also incorporates recent advances in knowledge of thrombosis and the newer oral anticoagulants
* Contains the very latest clinical treatments
* Includes updated illustrations and clinical photographs to illustrate concepts and aid understanding
* Features extensive online self-assessment at www.ataglanceseries.com/haematology
This book is an invaluable resource for medical students and health professionals wanting to consolidate and expand their knowledge of haematology.