Microelectrofluidic Systems is visionary in its leverage of electronic design principles for microsystem design and heralds a new era of automated system-on-a-chip (SOC) design. The strategy it presents holds the potential for significant reductions in design time and maintenance costs, and its techniques and tools can lead to the high-volume production needed for the inevitably growing product market. Integrating top-down and bottom-up design philosophies, this strategy supports modeling and simulation from the component level to the system level and leads to optimization tools valuable in design tasks from conceptualization to final manufacturing.

Tianhao Zhang, Krishnendu Chakrabarty, Richard B. Fair

INTRODUCTION. Review of State-of-the-Art. Research Motivation. Research Objective. HIERARCHICAL MODELING. Dynamic Modeling and Simulation at Circuit Level. MEFS System-Level Modeling and Simulation. Conclusion. HIERARCHICAL INTEGRATED DESIGN ENVIRONMENT WITH SYSTEMC. Suitability of Modeling Languages for Hierarchical Design. Building Design Environmental with SystemC. Conclusion. SYSTEM-LEVEL HIERARCHICAL SIMULATION AND PERFORMANCE EVALUATION. Hierarchical Modeling and Simulation Methodology. Micro-Chemical Handling System. System Performance Analysis and Design Optimization. Conclusion. CIRCUIT-LEVEL HIERARCHICAL OPTIMIZATION. Simulation Design Methodology. Optimization Verification. On-Target Design Optimization. Robust Design Optimization. Application Flexibility Optimization. Conclusion. PERFORMANCE COMPARISON WITH SYSTEMC ENVIRONMENT. Introduction. Continuous-Flow PCR System. Droplet-Based PCR System. Comparison Between Continuous-Flow PCR and Droplet PCR. Conclusion. CONCLUSION.