Discussing different aspects of the philosophy of Gilbert Simondon, Raymond Ruyer, Gilles Deleuze and Felix Guattari, and including some contemporary thinkers, such as Catherine Malabou, Bernard Stiegler, Bruno Latour, and Donna J. Haraway, Audrone Zukauskaite argues that all these threads can be seen as precursors to organism-oriented ontology. Rather than concentrating on individuals and identities, contemporary philosophy is increasingly interested in processes, multiplicities and potential for change, that is, in those features that define living beings. Zukauskaite argues that the capacity of living beings for self-organisation, creativity and contingency can act as an antidote to biopolitical power and control in the times of the Anthropocene.