Exciting advances are occurring in the understanding of the molecular pathogenesis of squamous head and neck cancers. Epidemiology, staging and screening, as well as premalignancy, chemoprevention and the molecular biology of head and neck cancer, lay the groundwork for the understanding of the clinical chapters that follow. Controversial treatments will be compared to the standard management of patient care. Therapy chapters are divided into stage or category specific (resectable advanced, unresectable advanced or metastatic) problems, allowing the reader to review the current standards and options for patient types or specific patients easily. Considerations of supportive care, late toxicities and quality of life, often overlooked are reviewed in detail.
This is a comprehensive summary of the current state of the art research and treatment.

Overview of Head and Neck Cancer.- Epidemiology, Staging, and Screening of Head and Neck Cancer.- Oral Preneoplasia and Chemoprevention of Squamous Cell Carcinoma of the Head and Neck.- Early Stage Head and Neck Cancer - Surgery.- Radiation Therapy in the Management of Early-Stage Head and Neck Cancer.- Advanced Head and Neck Cancersurgery and Reconstruction.- Modified Fractionated Radiotherapy in Head and Neck Squamous Cell Carcinoma (HNSCC) & Re-Irradiation in Recurrent Head and Neck Carcinomas.- Organ Preservation-Induction Chemotherapy.- Organ Preservation for Advanced Head and Neck Cancer Concomitant Chemoradiation.- Unresectable, Locoregionally Advanced Head and Neck Cancer.- Nasopharyngeal Cancer.- Treatment of Metastatic Head and Neck Cancer: Chemotherapy and Novel Agents.- New Therapies for Locoregionally Advanced and Locoregionally Recurrent Head and Neck Cancer.- Quality of Life and Late Toxicities in Head and Neck Cancer.- Oral, Dental, and Supportive Care in the Cancer Patient.