Anti-Angiogenic Cancer Therapy provides information on the process of angiogenesis and its role in tumor growth and metastasis. It compiles the work of leading experts to explore angiogenesis inhibitors under clinical investigation, as well as early agents used in preclinical studies. It discusses the unique aspects of targeting and inhibiting angiogenesis and the challenges associated with clinical development of angiogenesis inhibitors including trial design and surrogate marker endpoints. The chapters are organized to allow readers easy access to the fundamental concepts of angiogenesis and information on the complexities associated with targeting angiogenesis for specific types of cancer.

Angiogenesis in Cancer; Targeting Angiogenesis for Cancer Therapy; Translating Angiogenesis Inhibitors to the Clinic; Treatment of Specific Cancers with Angiogenesis Inhibitors

Darren W. Davis, Roy S. Herbst, James L. Abbruzzese