This book brings together new insight and research on mechanical, mathematical, physical, and biological approaches for simulating the behavior of cells, specifically tumor cells. It illustrates how phenomena occurring at various scales can be modeled and coupled to account for multiscale aspects. The text links subcellular effects to cellular properties, covers the modeling of cell migration and multicellular systems, and examines cell interactions with the environment, such as the rolling motion of leukocytes on a vessel wall and the forces exerted by cells on a rigid substrate.

From Subcellular to Cellular Properties. Single Cell Migration Modeling. Mechanical Effects of Environment on Cell Behavior. From Cellular to Multicellular Models. Index.

Arnaud Chauviere is an assistant professor of health informatics in the Health Science Center at the University of Texas in Houston.

Luigi Preziosi is a professor of mathematical physics at the Politecnico di Torino in Italy.

Claude Verdier is a research director at CNRS in Grenoble, France.