1. The Basic Biology of Metastasis.- 2. Clinical Aspects of Bone Metastases in Prostate Cancer.- 3. Animal Models of Bone Metastasis.- 4. MIP-1 Alpha and Myeloma Bone Disease.- 5. Type I Collagen-Mediated Changes in Gene Expression and Function of Prostate Cancer Cells.- 6. PTHRP and Skeletal Metatasis.- 7. OPG, RANKL, and RANK In Cancer Metastasis: Expression and Regulation.- 8. Matrix Metalloproteinaess and Bone Metastasis.- 9. Endothelins in Bone Cancer Metastases.- 10. Bisphosphonate Actions on Bone and Visceral Metastases.- 11. Gene Therapy for Prostate Cancer Bone Metastasis.- 12. Cancer Cells Homing to Bone: The Significance of Chemotaxis and Cell Adhesion.- 13. Histological, Immunophenotypic and Histomorphometric Characterization of Prostate Cancer Bone Metastases.

- National Cancer Institure Budget is encouraging research in order to develop a better understanding of metastasis of cancer to the bone

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