This volume is a eoLleetion of manuseripts based on presenta­ tions at a symposium "Polymerie Separation Media" organized for the Seeond Chemieal Congress of the North Ameriean Continent held in Las Vegas, August 24-29, 1980. The symposium was organized to bring together researehers in the expanding field of separations based on polymerie media. A diverse eross-seetion of re.seareh areas were presented, whieh were linked by the aetive separation agent being a polymerie material. I would like to thank the authors for their endeavours and the audienee for their partieipation, espeeially in light of the late change of venue for this meeting. Finally I am indebted to the Division of Polymer Chemistry Ine. of the Ameriean Chemieal Soeiety for their sponsorship. Anthony R. Cooper, Ph.D., FRSC Palo Alto, California July 1981 v CONTENTS DEDICATION TO BAREND H. J. HOFSTEE . . . . . . . . . . . .. . . 1 PART I TRANSPORT IN POLYMERIC MEDIA Some Condiserations Regarding the Hyperfi1teration of Organic Liquids. 7 I. J. Bass and P. Meares Measurement of Transport Interaction in Membranes . . . . . . . . . . . . . . 19 . . . K. S. Spiegier, T. S. Brun and A. Berg Free Vo1ume Estimates in Crysta11ine and Fi11ed Polymers . . .. .............. 21 H. L. Frisch and A. I. Kreituss Diffusion Coefficients of Po1ystyrenes in Porous Gels From Mass Transfer Dispersion in Gel Permeation Chromatography . . . . . . . . . . . . . . . . . . 27 . . . .

I Transport in Polymeric Media.- Some Condiserations Regarding the Hyperfilteration of Organic Liquids.- Measurement of Transport Interaction in Membranes.- Free Volume Estimates in Crystalline and Filled Polymers.- Diffusion Coefficients of Polystyrenes in Porous Gels From Mass Transfer Dispersion in Gel Permeation Chromatography.- Mechanism of Gas Permeation Through Porous Polymeric Membrane.- Composite Hollow Fiber Membranes for Gas Separation: The Resistance Model Approach.- II Functionalized Polymers as Separation Media.- Purification of Enzymes by Affinity Chromatography.- Hydrophobic and Other Non-Ionic Parameters in Protein Separation and Adsorptive Immobilization by Substituted Agaroses.- Use of Synthetic Chemical Ligands for Affinity Chromatography of Proteins.- Separation of Amines and Acids by Sterically Hindered Polymers.- Polymeric Separation Media. New Functionalized Polymers for the Selective Removal of Haptens from Complex Organic Mixtures.- Comparative Performance of Microparticulate Packings for Aqueous Steric Exclusion Chromatography.- III Polymeric Membranes as Separation Media.- Effluent Free Electrolytic Regeneration of Ion Exchange Resins.- An Ultrafiltration Device for Free/Bound Drug Analysis.- Microporous Membranes and Crossflow Filtration of Macromolecules and Particles.- Purification of Polymeric Dyes by Ultrafiltration.- Physico-Chemical Characterization of Enzyme - Loaded Cellulose Acetate Membranes.- IV Novel Polymeric Separation Media: Structure and Properties.- Novel Water Treatment Processes Which Involve Polymers.- Synthesis and Thermal Regeneration of Polymeric Crown Ethers.- Ion-Selective Polymeric-Membrane Electrodes with Immobilized Ion-Exchange Sites.- Characterization of Polyacrylamide Gels by Dynamic Light Scattering Underthe Microscope.- Thermal Crosslinking of a Chemically-Modified Ionomer.- Characterization of Ionically Crosslinked Polyacrylic Acid Membranes.- List of Contributors.