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I. Prostaglandin Biochemistry and Assays.- 1. Biosynthesis and Metabolism of Prostaglandins in Human Kidney in Vitro.- 2. Regulation of Prostaglandin Biosynthesis in Cultured Renal Medullary Interstitial Cells.- 3. Cellular Compartmentalization of the Biosynthesis and Function of PGE2 and PGI2 in the Renal Medulla.- 4. Regional Differences in in Vitro Prostaglandin Synthesis by the Rat Kidney.- 5. Biosynthesis of Prostaglandins and Thromboxanes in the Dog Kidney.- 6. Distinct Acylhydrolase and PG Synthase Systems in the Perfused Rabbit Kidney: Selective Activation by Vasoactive Peptide Hormones and by Adenine Nucleotides.- 7. Perfusion-Dependent, Selective Induction of Prostaglandin Biosynthesis Activity in Rabbit Kidney Cortex.- 8. Investigations of Renal Arachidonic Acid Metabolites by Radioimmunoassay.- 9. Investigations on Renal Prostaglandins by Gas Chromatography-Mass Spectrometry.- II. Physiology and Pathophysiology.- 10. The Role of Arachidonic Acid Metabolism in the Modulation of Renal Blood Flow.- 11. Reversal of Vasoconstriction in the Isolated Perfused Rat Kidney by Picogram Amounts of PGE2.- 12. Studies of Prostaglandin Action on the Glomerular Microcirculation.- 13. Tubular Actions of Arachidonic Acid Metabolites: Effects of NaCl and Water Transport.- 14. The Effects of Vasopressin and Vasopressin Analogues upon Renal Synthesis of Prostaglandins.- 15. Renal Prostaglandins in Human Adaptation to Modifications of Sodium Balance.- 16. Cardiovascular Responses to 6-Keto-PGE1, a Potent Renin-Releasing Agent.- 17. Neural Control of Renin Secretion: Role of Prostaglandins.- 18. Factor Affecting Excretion of Renal Prostaglandins. A Study with Hypertonic Sodium and Glucose Infusions in Normal Female Subjects.- 19. Prostaglandin E2 (PGE2) in Renal Papilla in NaClHypertension.- III. Pharmacology and Pathopharmacology.- 20. Diuretics and Kidney Prostaglandins.- 21. Does Prostaglandin Release Contribute to the Hypotension Induced by Inhibitors of Angiotensin Converting Enzyme?.- 22. The Mode of Action of Anti-inflammatory Steroids.- 23. Mechanism of Steroid-Induced Inhibition of Prostaglandin Production by Rat Renomedullary Cells in Culture.- 24. The Effect of Indomethacin on Renal Function and Glomerular Protein Loss.- 25. The Role of Arachidonic Acid Metabolites in the Functional Renal Impairment Associated with Liver Disease.- 26. Prostaglandins and Renal Function after Chronic Ligation of the Common Bile Duct in Dogs.- 27. The Influence of Indomethacin on Some Pharmacological Actions of Atenolol.- IV. Clinical Applications.- 28. The Mechanism and Site of the Enhanced Arachidonate Metabolism in Ureter Obstruction.- 29. Role of Thromboxanes in Renal Disease.- 30. Platelet and Vascular Prostaglandins in Uremia and Thrombotic Microangiopathy.- 31. Platelet Prostaglandin Production in the Nephrotic Syndrome.- 32. The Pathophysiologic and Therapeutic Role of Platelet and Vascular Arachidonic Acid Metabolites in Renal Failure.- 33. The Role of Arachidonic Acid Metabolites in the Pathophysiology of Bartter's Syndrome.- 34. Abnormal Platelet Aggregation in Patients with Bartter's Syndrome.- 35. A Possible Role of Arachidonic Acid Metabolites in Essential Hypertension.- 36. The Role of Renal Prostaglandin E in the Mechanism of the Exaggerated Fractional Na Excretion in Hypertensive Patients with Advanced Renal Disease.- 37. Platelet Deposition in Renal Transplant Rejection and Treatment with Prostacyclin Infusion.- 38. Factors Affecting Immunoreactive Thromboxane B2 in Kidney Transplant Patients.