This work is devoted to the late Ukrainian computer scientist V. M. Glushkov on the 90th anniversary of his birthday. Dr. Glushkov is known for his contribution to the world computer science and technology and this volume analyzes the ideas and paths of development of informatics formulated by him and demonstrate their important role in constructing computer technologies of basic research in the fields of applied mathematics, theories of computer programming and computing systems.
A significant portion of the monograph is devoted to the elucidation of new results obtained in the field of mathematical modeling of complicated processes, creation of new methods for solving and investigating optimization problems in different statements and development of computer technologies for investigations in the field of economy, biology, medicine and information security in systems.
The monograph will be of particular interest to informatics specialists and experts using methods of informatics and computer technologies to investigate complicated processes of different natures and developing new information technologies. It may also be useful for both graduate students and postgraduates specializing in Computer Science.

Ivan Sergienko is the director of the V.M. Glushkov Institute of Cybernetics of National Academy of Sciences of Ukraine. He received the State Prize for Science in Technology in 1972 and the SSSR State Prize in 1981. He was awarded the V. M. Glushkov Prize for Cybernetics, Computer Machine and Systems Theory in 1986, and elected an academician in 1988. He is the author of Springer titles "Methods of Optimization and Systems Analysis for Problems of Transcomputational Complexity" and "Optimal Control of Distributed Systems with Conjugation Conditions," and is also the editor of Springer journal "Cybernetics and Systems Analysis."

Introduction.- 1. Theoretical and Applied Programming.- 2. Supercomputers and Intelligent Technologies of High-Performance Computing.- 3. Computer Technologies as Tools for Studying Complicated Processes.- 4. Mathematical Models and Computer Technologies in Investigating Economic Processes.- 5. Mathematical Modeling and Investigation of Complicated Processes.- 6. Optimization Methods for Solving Transcomputational Problems.- 7. Combinatorial Optimization Problems.- 8. Computer Technologies in Medical and Biological Research.