Essential resource for the fight against emerging infectious diseases
Incidences such as the 2014 Ebola epidemic in West Africa and the 2015 appearance of Zika in Brazil provide dramatic evidence of the continued ability of microbes to emerge, spread, adapt, and threaten global health. The challenge facing infectious disease specialists and public health professionals is to improve and find new diagnostic, therapeutic, and prevention strategies.
The editors of the 10th installment of the Emerging Infections series have compiled the perspectives of leading infectious disease experts into 22 chapters that provide important updates on a broad range of emerging and reemerging bacterial, viral, parasitic, and fungal infectious diseases in the United States and globally. In addition to focusing on MERS, Ebola virus disease, chikungunya, and Zika virus disease, Emerging Infections 10 explores the global threat of antimicrobial resistance in reviews on carbapenem-resistant Enterobacteriaceae, multiply-resistant gonococcal infections, non-typhoidal Salmonella infections, and artemisinin-resistant Plasmodium falciparum malaria. Topics include both recently- and long-recognized diseases that pose challenges for the clinical, laboratory, research, public health, and animal health communities.
Emerging Infections 10 presents new and emerging strategies to prevent, control, and eradicate infectious diseases and guides readers to the primary literature where they can explore individual topics in greater depth. This book is a valuable reference for professionals in microbiology, epidemiology, public health, and clinical and veterinary medicine.

Contributors ix
Foreword xv
Preface xvii
Acknowledgments xix
1 West Africa 2013: Re-examining Ebola 1
Daniel G. Bausch and Amanda Rojek
2 Preparing for Serious Communicable Diseases in the United States: What the Ebola Virus Epidemic Has Taught Us 39
Jay B. Varkey and Bruce S. Ribner
3 Ebola Virus Disease: Therapeutic and Potential Preventative Opportunities 53
Robert Fisher and Luciana Borio
4 Middle East Respiratory Syndrome (MERS) 73
Sonja A. Rasmussen, Amelia K. Watson, and David L. Swerdlow
5 The Emergence of Enterovirus D-68 105
Kevin Messacar, Mark J. Abzug, and Samuel R. Dominguez
6 The Role of Punctuated Evolution in the Pathogenicity of Influenza Viruses 121
Jonathan A. McCullers
7 Measles in the United States since the Millennium: Perils and Progress in the Postelimination Era 131
Anne Schuchat, Amy Parker Fiebelkorn, and William Bellini
8 Chikungunya Virus: Current Perspectives on a Reemerging Virus 143
Clayton R. Morrison, Kenneth S. Plante, and Mark T. Heise
9 Zika Virus Disease 163
Werner Slenczka
10 West Nile Virus Infection 175
James J. Sejvar
11 Mobilization of Carbapenemase-Mediated Resistance in Enterobacteriaceae 201
Amy Mathers
12 Antimicrobial Resistance Expressed by Neisseria gonorrhoeae: A Major Global Public Health Problem in the 21st Century 213
Magnus Unemo, Carlos del Rio, and William M. Shafer
13 Bordetella holmesii: Still Emerging and Elusive 20 Years On 239
Laure F. Pittet and Klara M. Posfay-Barbe
14 Cronobacter spp. 255
Brian P. Blackwood and Catherine J. Hunter
15 Clostridium difficile Infection 265
Jae Hyun Shin, Esteban Chaves-Olarte, and Cirle A. Warren
16 Emerging Tick-Borne Bacterial Pathogens 295
Tahar Kernif, Hamza Leulmi, Didier Raoult, and Philippe Parola
17 Bordetella pertussis 311
Delma J. Nieves and Ulrich Heininger
18 Invasive Infections with Nontyphoidal Salmonella in Sub-Saharan Africa 341
Barbara E. Mahon and Patricia I. Fields
19 Fungal Infections Associated with Contaminated Steroid Injections 359
Carol A. Kauffman and Anurag N. Malani
20 Emerging Fungal Infections in the Pacific Northwest: The Unrecognized Burden and Geographic Range of Cryptococcus gattii and Coccidioides immitis 375
Shawn R. Lockhart, Orion Z. McCotter, and Tom M. Chiller
21 The Emerging Amphibian Fungal Disease, Chytridiomycosis: A Key Example of the Global Phenomenon of Wildlife Emerging Infectious Diseases 385
Jonathan E. Kolby and Peter Daszak
22 Artemisinin-Resistant Plasmodium falciparum Malaria 409
Rick M. Fairhurst and Arjen M. Dondorp
Index 431