Part I. Introduction.- Mathematical and physical modeling principles of complex biological systems.- Part II. Blood.- Vascular Anatomy and Physiology of the Eye.- Pathological Consequences of Vascular Hemodynamic Alterations in the Eye.- Measurement of geometrical and functional parameters related to ocular blood flow.- Mathematical modeling of blood flow in the eye.- Part III. Aqueous Humor.- Changes in Parameters of Aqueous Humor Dynamics Throughout Life.- Aqueous Humor Dynamics and its Influence on Glaucoma.- Approaches to Aqueous Humor Outflow Imaging.