1 Biochemical Engineering and Biotechnology.- 1.1 Biochemical Engineering and Biotechnology-An NSF Perspective.- 1.2 Use of Fluorometry for On-Line Monitoring and Control of Bioreactors.- 1.3 Computer Control of Glutamic Acid Production Based on Fuzzy Clustering of Culture Phases.- 1.4 National Science Foundation Engineering Centers Division- Biotechnology and Bioengineering Research Centers.- 1.5 The Effect of Glutathione Depletion in the Glutamine Synthetase Gene Amplification System.- 1.6 Modeling Vapor Phase Water Droplet Extraction of Proteins from the Medium of an Air Fluidized Bioreactor.- 2 Applied Genetic Engineering.- 2.1 Genetic Engineering and Protein Engineering on Chymosin and Mucor Rennin.- 2.2 Genetic Engineering of Carbon and Energy Metabolism.- 2.3 Microbial Production of Useful Compounds with recDNY Technique.- 2.4 Amplification of Homologous Fermentative Genes in Clostridium Acetobutylicum ATCC 824.- 2.5 Cloning and Sequencing of the Alcohol Dehydrogenase Gene from Bacillus stearothermophilus and Alteration of the Optimum pH of the Enzyme by Protein Engineering.- 2.6 Bioprocess Kinetics and Optimization of Recombinant Fermentation: Genetic and Engineering Approaches.- 3 Biocatalysis.- 3.1 Comparison of Primary, Secondary and Tertiary Structures of Xylanase of Bacillus pumilus and Cellulase of Aspergillus acleatus.- 3.2 Synthesis of Chiral Intermediates for D-Pantothenate Production by Microbial Enzymes.- 3.3 Mechanistic Aspects of Enzymatic Catalysis in Anhydrous Organic Solvents.- 3.4 Construction of a Novel Biocatalyst Based on an Organelle Model-Expression of the Latent Function of the Enzyme by Organized Assemblies.- 3.5 Enzyme Catalysis in Unusual Environments.- 3.6 Preparation and Characterization of Semisynthetic Oxidases.- 4 Bioprocess Engineering.- 4.1 On-line Diagnosing System for Fed-Batch Fermentation.- 4.2 Sensors for Bioprocess Monitoring and Control.- 4.3 Development of Micro-Biosensors for Brain Research.- 4.4 Application of 2-D Gel Electrophoresis to Study Intracellular Events in Industrial Fermentations.- 4.5 A Knowledge-Based Approach for Control of Phenylalanine Pro¬duction by a Recombinant Eschirichia coli.- 4.6 Modulator Sorption in Gradient Elution Chromatography.- 5 Cell Culture.- 5.1 Strategies for Improving Productivity in Plant Cell, Tissue, and Organ Culture in Bioreactors.- 5.2 Genetic Engineering of Medicinal Plants.- 5.3 Engineering Growth Factor/Receptor Processes: Effects of EGF Receptor Trafficking Dynamics on Cell Proliferation Responses to EGF.- 5.4 The Effect of Light Irradiation on Secondary Metabolite Production by Coffea arabica Cells.- 5.5 A Model for Embryo Development in Dicotyledonous Plants.- 5.6 Kinetics of Hybridoma Cell Growth in Continuous Culture.- 5.7 Development of New Immobilization Method and Continuous Pro¬duction of Bioproducts in Immobilized Mammalian Cell System.