Isatin is an important scaffold in organic synthesis because of it shows various biological activities. The most attractive application of isatin in organic synthesis is undoubtedly owing to the highly reactive C-3 carbonyl group. Many aromatic compounds consist of the isatin moiety have stimulating applications in the field of drug discovery, industry and in biology. By using of Green chemistry, Synthesis of different derivatives of these scaffolds has been achieved in water as the reaction medium. This content defines the water-mediated synthesis of various isatin based aromatic compounds.

Mayuri A. Borad was born in Junagadh (Gujarat) India in 1990. She obtained her M.Phil. degree in organic chemistry in 2013 from the Gujarat University, Ahmedabad (India). She is pursuing her Ph.D. under Dr. Hitesh D. Patel at Gujarat University, Ahmedabad. Her research work focuses on spiro heterocyclic compound and multicomponent reactions.