Oxadiazole and its derivatives have been focused on for their broadly chemical and biological importance in a previous couple of years. Now a time developments in medicinal chemistry 1,3,4 oxadiazole bring out as most bio-diverse interesting nucleus and occupy unique role. On this description of introduction we summarized that 1,3,4 oxadiazole is come out as a highly reacted and more efficient scaffold than other. Their flexible bonding toward other moieties and extensively therapeutic action attract to us. Oxadiazole is a useful ring in the biological active compound. This moiety has four different structures which depend on the position of nitrogen. Among these, 1,3,4-oxadiazole is a very useful ring for therapeutic interest. 1,3,4-oxadiazole have various biological activity, for example, Anti-HIV, Anticancer, Antioxidant, Antimicrobial, Anti-inflammatory etc. this article is review the literature work described by researchers on 1,3,4-oxadaizole moiety for their biological activity.

Dr. Vikram Panchal secured a master degree in Inorganic Chemistry. His doctoral research is in Organic chemistry. He has worked as an assistant professor in Sal Eductional campus.