Brain disorder is mainly originated from the abnormal secretion of neurotransmitters which are all biogenic amines. A neurotransmitter is a signaling molecule secreted by a neuron to affect another cell across a synapse. The cell receiving the signal, any main body part, or target cell, may be another neuron, but could also be a gland or muscle cell. Neurotransmitters are released from synaptic vesicles into the synaptic cleft where they are able to interact with neurotransmitter receptors on the target cell. The neurotransmitter's effect on the target cell is determined by the receptor it binds. Many neurotransmitters are synthesized from simple and plentiful precursors such as amino acids, which are readily available and often require a small number of biosynthetic steps for conversion. Neurotransmitters are essential to the function of complex neural systems. The exact number of unique neurotransmitters in humans is unknown, but more than 100 have been identified. Common neurotransmitters include glutamate, GABA, acetylcholine, glycine and norepinephrine, dopamine, serotonin, histamine etc. Neurotransmitters relay their messages by traveling between cells.

Prof Dr Dhrubo Jyoti Sen, School of Pharmacy, Techno India University, Kolkata; Dr Dhananjay Saha as Deputy Director, West Bengal Technical Education & Kushal Nandi did BPharm from School of Pharmacy, Techno India University, WB having 100 publication in International Journals with 14 Best Paper Awards, presently doing MPharm in JIS University, WB.