Vnekletochnyj matrix (ECM) - äto nekletochnyj komponent, prisutstwuüschij wo wseh tkanqh i organah, kotoryj obespechiwaet ne tol'ko wazhnuü fizicheskuü osnowu dlq kletochnyh komponentow, no i iniciiruet wazhnejshie biohimicheskie i biomehanicheskie signaly, neobhodimye dlq remodelirowaniq tkanej. Jeto wysokodinamichnaq trehmernaq makromolekulqrnaq struktura, sostoqschaq iz kollagenow, proteoglikanow, glikozaminoglikanow, älastina, fibronektina, lamininow i nekotoryh drugih glikoproteinow, kotoraq postoqnno remodeliruetsq fermentatiwno ili nefermentatiwno, a ee molekulqrnye komponenty podwergaütsq ogromnomu kolichestwu posttranslqcionnyh modifikacij. Blagodarq ätim fizicheskim i biohimicheskim harakteristikam JeCM sposoben formirowat' biohimicheskie i mehanicheskie swojstwa razlichnyh organow, takie kak prochnost' na rastqzhenie i szhatie, älastichnost', a takzhe obespechiwaet zaschitu za schet bufernogo dejstwiq, podderzhiwaüschego wnekletochnyj gomeostaz i uderzhanie wody.

I am Dr. Salil Joshi, Post Graduate student, Department of Periodontology, Subharti Dental College & Hospital, Meerut. I would like to pay my sincere gratitude to my guide and mentor Dr. Mayur Kaushik , Professor and Head for his relentless insight, professional excellence and unparalleled support.