Part 1 The Presentations: Introduction to the Presentations.-Women Between Biology and Civilization/Zwischen Biologie und Kultur - Das HRT Dilemma.-Issues with the Term Responsibility/Probleme des Verantwortungsbegriffs im Spannungsfeld von Pharmaforschung und ärztlichem Handeln.- Epidemiological synopsis of selected chronic diseases in women.- Synopsis on Endometrial Changes in HRT.- Pathology of Colon and Ovary/HRT und Karzinome des Ovars und Kolon.-The Progenitor Cell Model and its Impact on the Understanding of Regeneration of Normal Breast Epithelium and Proliferative Diseases.- Indications for Menopausal Hormone Therapy.- HRT and Cardiovascular Disease in Women.-Hormonersatztherapie und kardiovaskuläre Erkrankungen.-The One Million Women Study.- Paradigm Shift in Causal Thinking in Epidemiology.-Perception and Communication of Risk/Rezeption und Kommunikation von Risiken.- Some thoughts on the Workshop.- Part 2 - The General Discussion: Menopause and Breast Cancer.-Bones and Joints.-Menopause and Colon Cancer.-Cancer of Ovary /Endometrium.-Brain and Mental Aspects.-Cardiovascular Outcomes.-Discussion on Further Studies.- Part 3 : Conclusions of the 'Kloster Andechs' Workshop.-Summary of Workshop Results

This volume contains an advanced level discussion on the appropriateness of hormone replacement therapy (HRT) in modern postmenopausal women on the basis of evidence provided by recent epidemiological studies. It addresses all aspects of benefits and risks associated with HRT. It focuses, however, on cancer risk and on risk of breast cancer in particular. The book advocates further epidemiological studies which incorporate pathobiological assessments.